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Name: Mitogen-activated protein kinase 1 - mouse
Alternative names: Erk2, p42-MAPK, MAPK2
Taxonomy: [Mus musculus] Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Coelomata; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus.
Protein Size: 358 aa
mRNA Size: 5099 bp
MW: 41276 Da
pI: 6.5
Activator MKKs: MAP2K1 (MEK1); MAP2K2 (MEK2)
Activation site: TEY (pThr-183 and pTyr-185)
Protein sequence [FASTA]:
>mkr|MUM000001|MK1_MOUSE|Mitogen-activated protein kinase 1 MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQ TYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLS NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG ILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRI EVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
Cross references
RefSeq: Protein: NP_001033752.1.
Nucleotide sequence: NM_001038663.1.
RefSeq: Protein: NP_036079.1.
Nucleotide sequence: NM_011949.3.
NCBI Gene: 26413 [ MAPK1 mitogen-activated protein kinase 1 ]
UniProtKB: P63085 [ MAPK1 ]